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Liquid Chromatography (LC) Based Analysis Services

Liquid Chromatography (LC) is a form of chromatography that allows separation of complex mixtures of both semi- and non-volatile compounds based on slight differences in solubility between chemicals. This technique is a complementary to GC but effective when the compounds of interest are not volatile or are thermally labile. Liquid Chromatography (LC) Based Analysis Services at Creative Proteomics offers you a state-of-the-art liquid separations platform that includes standard LCs with frequently used separation mechanisms.

Highlight:

Agilent Ion Trap LC-MS system: The system combined with a UV detector was able to collect MS and UV data, which facility the analysis of various components. Such as polymer additives, degradents, pharmaceutical impurities, and active pharmaceutical ingredients.
Custom Sercices: Development and/or validation of analytical methods specific to your sample matrix, active ingredient and desired instrumentation.

We are Capable of:

Analysis of Residues for Identification
Coatings Characterization
Determination of Residual Acrylamide Content
Impurity Identification
Leachables and Extractables Analysis
Surfactant Analysis
Polymer Additive Analysis and Quantitation
Protein and Amino Acid Characterization
Residual Monomer and Oligomer Detection
Method Development and Validation

Detection Techniques:

Liquid Chromatography (LC)
Liquid Chromatography Mass Spectroscopy (LC-MS)
Tandem LC Mass Spectroscopy (LC/MS/MS)
Liquid Chromatography-Multiple Reaction Monitoring Mass Spectrometry (LC-MRM)
Liquid chromatography quadrupole time-of-flight mass spectrometry (LC-Q-TOF-MS)
Triple Quadrupole Liquid Chromatography Mass Spectrometry
Ion trap LC/MS/MS
MOLDI TOF MS LC/MS
Nano electrospray liquid chromatography tandem mass spectrometry (Nano-ESI-LC-MS-MS)
2D-nano-LC-ESI LTQ-Orbitrap MS/MS

Creative Proteomics's analytical scientists are highly experienced and knowledgeable in the application of LC-MS analyses to a wide variety of industries ranging from Food & Beverage to Pharmaceuticals and much more. Experience, fast turnaround, clear concise written reports, and custom service are provided to help customers resolve your analytical and technical challenges.

* For Research Use Only. Not for use in diagnostic procedures.

Our customer service representatives are available 24 hours a day, 7 days a week. Inquiry

From Our Clients

"I recently used their proteomics service for a project analyzing protein interactions in yeast models. The team was very responsive and helped clarify the methodology they employed, which made me feel confident in the results. The data quality was solid, with clear identification of several key proteins involved in our study. Their thorough analysis enabled me to pinpoint specific interactions that I hadn't considered before, which significantly improved the direction of my research. I appreciate their professionalism and support throughout the process."

Sarah Thompson, University of California, Berkeley

"Our lab collaborated with them on a project studying cancer biomarkers. The proteomics analysis provided was detailed and focused, specifically highlighting the differential expression of proteins between healthy and tumor samples. Their clear explanations of the data helped my team understand the biological implications. I also appreciated their willingness to revise the reports based on our feedback, ensuring that we had everything we needed for our publication. This collaborative spirit was invaluable."

Emily Rodriguez, Stanford University

"Our lab worked with them on a project studying the effects of diet on gut microbiota using proteomics. They used a label-free quantification method to analyze proteins in fecal samples before and after dietary intervention. The results showed significant changes in protein expression linked to microbial activity. This was pivotal for our hypothesis about diet-microbiota interactions. The clarity of their data presentation made it easy for our team to integrate these findings into our ongoing research."

Dr. Lisa Wong, University of Toronto

"My experience with Creative Proteomics during the mass spectrometry analysis was excellent. We sent in human saliva and mouse brain tissue samples, which they expertly analyzed using both LC-MS and GC-MS techniques. The results were invaluable, revealing key metabolites in the saliva and identifying biomarkers linked to brain function in the brain tissue."

Dr. Emily Carter, Senior Research Scientist

"The overall service from Creative Proteomics was outstanding. They made the entire process seamless and efficient, allowing us to focus on our research. We worked with leaf and root samples from various Arabidopsis genotypes for targeted metabolomics analysis. Their thorough profiling of primary and secondary metabolites gave us important insights into how the plants respond metabolically to environmental stress."

Dr. Laura Henderson, Plant Physiologist

"We had a pleasant collaboration with Creative Proteomics on mass spectrometry analysis of lipids. They conducted a detailed analysis of lipid species, providing us with important insights into lipid metabolism and its relationship with metabolic syndrome disease states."

Dr. Sarah Mitchell, Research Scientist

Online Inquiry

Please submit a detailed description of your project. We will provide you with a customized project plan to meet your research requests. You can also send emails directly to for inquiries.

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