Enhancing Lyme Disease Research and Diagnostics through LC-MS-based Metabolomics
About the Poster
Ticks are vectors for a variety of pathogens, including Borrelia burgdorferi, the causative agent of Lyme disease, and Staphylococcus aureus, a common bacterial pathogen. The role of recombinant I. scapularis with a Reeler domain (PIXR) is a recombinant protein with potential antibacterial properties, and its effects on various bacterial strains and tick gut microbiota are of interest. This study aims to To evaluate the impact of rPIXR on bacterial viability, biofilm formation, and gut microbiota composition, employing advanced molecular biology techniques and metabolomic analyses facilitated by Creative Proteomics.
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