Protein Post-Translational Modifications in Disease Research
Disruption of PTMs can lead to the dysfunction of important biological processes, which can result in a variety of diseases. Thus, the footprints of PTM dysregulation can be seen in many diseases.
Protein Post-Translational Modifications in Viruses
PTMs of viral proteins are essential for regulating viral biological processes, including the production of infectious viral particles, viral infection, and so on. The study of PTMs of viral proteins contributes to the identification of effective diagnostic markers and the development of antiviral drugs.
Protein Post-Translational Modifications in Drug Discovery and Development
PTMs largely enrich the complexity of the proteome and clearly constitute a potential large subset of the biological space. In structure-based drug design, PTMs can be a bridge between an almost infinite chemical and biological space.
Protein Post-Translational Modifications in Plants
Protein PTMs are central to the regulation of numerous cellular and physiological processes in plants through their impact on protein stability, gene expression, signaling, and interactions, and enzyme kinetics.
