The octopus secretes venom from the posterior salivary gland, and its bite can cause pain and even fatal lesions. According to current research and analysis of octopus-related species, the proteome of octopus venom may contain a mixture of antimicrobial peptides, neurotoxins, etc., and contains new venom proteins/peptides that are different from other animal venoms. Therefore, new toxins from octopus may be more helpful for drug development.
Creative Proteomics provides octopus venom solutions through proteomics methods, analyze the comprehensive proteomic characteristics of the venom, and use a combination of transcriptomics and proteomics to identify and characterize putative toxins.
Octopus saliva research has always been a hot spot in venom research. Biochemical determination, molecular analysis, and toxicological research on them are very valuable for biological discoveries. Many types of octopus venom contain proteins/peptides with active characteristics, which can provide potential natural sources for the development of drug tools and disease treatment. In order to make better use of octopus venom, we use a combination of genomics, transcriptomics and proteomics to study octopus venom in detail.
Services | Technical Solutions |
---|---|
Samples | Capture → breed → dissect → sample |
Transcriptome | Extraction → homogenization → sequencing → assembly → function annotation → prediction |
Proteomics | Extraction → mass spectrometry analysis → database construction → identification → quantification |
Comprehensive analysis | Build heat map → estimate transcription level → match protein and transcriptome → homology analysis |
Venom has always been a potential source of drug discovery, and cephalopods, especially octopuses, have a rich variety and unique venom characteristics. We hope that through our professional understanding of venom, we can bring benefits to customers in the application of octopus venom to design of a series of anti-cancer, anti-viral, anti-bacterial, anti-inflammatory, analgesic and other drugs.
Creative Proteomics is a senior expert in the field of venom. We help clients complete their projects and successfully obtain effective and accurate venom research results. We provide customized services according to customer needs, please contact us for more information and detailed quotation.