The emergence of high-throughput omics technologies, such as transcriptomics, proteomics, and metabolomics, has revolutionized the study of venoms. They have facilitated large-scale data collection and analysis and can identify and characterize low-abundance venom components. With the continuous development of modern metabolomics techniques, such as liquid chromatography-mass spectrometry or gas chromatography-mass spectrometry, analyzing the metabolite spectrum of venom also helps to better understand the pathology and pharmacology of venom components.
So far, most animal venom studies are still focused on protein and peptide compounds, and there is no comprehensive report on the metabolome. The purpose of Creative Proteomics service is to use mass spectrometry-based metabolomics to identify and quantify the metabolites present in the venom of various toxic species such as snakes, scorpions, spiders, bees, etc. We applied two different MS-based methods. The first is to use non-targeted metabolomics, that is, high-resolution, accurate-mass MS to obtain a broad overview of the metabolic components of the venom, but no quantitative data. The second method is to quantify the metabolites in venom samples using targeted metabolomics methods. We also provide analysis services for some common metabolites of venom.
The technology of venom metabolomics based on MS has been developed rapidly. It can identify and quantify the existing metabolites for the venom, and it can not only help to study the presence of amines, amino acids, carbohydrates and organic acids in the venom, but also provide other metabolite types of venom components information.
Creative Proteomics has an advanced technology platform and rich service experience and can provide you with satisfactory venom research services. If you are looking for venom metabolomics research not mentioned on this website, please feel free to contact us via email or phone!