Glucose Analysis Service

What Is Glucose

Glucose is a sugar and the chemical molecular formula is C6H12O6. The name "Glucose" means sweet wine in the Greek language. The suffix "-ose" is a chemical classifier, meaning is a kind of carbohydrate. The D-Glucose, also named as dextrose, exists widely in nature, but the L-Glucose cannot occur naturally.

Glucose is a ubiquitous fuel in biology and is the most widely used as an energy source in most living organisms from bacteria to humans. The biochemical processes to convert Glucose into energy in the form of ATP are aerobic respiration,anaerobic respiration, or fermentation. Glucose can provide about 3.75 kilocalories (16 kilojoules) of food energy per gram through aerobic respiration and is the human body's main source of energy. Glucose can be got through the breakdown of carbohydrates. , Glucose is oxidized to eventually form CO2 and water, and is accompanied by the production of the energy mostly in the form of ATP through the citric acid cycle and oxidative phosphorylation. The concentration of Glucose in the blood can be regulated by the insulin and other mechanisms. The availability of Glucose has big influence on the psychological processes of the brain because the Glucose supplies almost all the energy for the brain.

High-Performance Liquid Chromatography (HPLC) Detection of Glucose and Its Oxidation Products

Currently, methods for the determination of sugar substances primarily include chemical methods, near-infrared spectroscopy, gas chromatography, and high-performance liquid chromatography (HPLC), among others. Near-infrared spectroscopy exhibits relatively lower accuracy, while gas chromatography for sugar substance determination requires derivatization, making it a more cumbersome process. HPLC-based methods for sugar substance determination offer several advantages, such as speed and accuracy, and have been widely applied in the analysis and detection of sugar substances in food and fruits. It is a common means of sugar substance analysis today.

What We Can Do for You

Creative Proteomics has established a mature platform for the quantitative detection of glucose and its oxidation products. This detection platform utilizes High-Performance Liquid Chromatography (HPLC) and biochemical methods to efficiently and accurately assess changes in glucose content. For rare sugar metabolites, if standard samples are provided, this platform can offer customized testing services. In cases where HPLC-based detection is not feasible for certain samples, our detection platform can provide tailored testing or reagent kit outsourcing services. Additionally, we offer various other sugar metabolite detection services to meet your specific requirements.

Technical Advantages

Isotope internal standard correction, absolute quantification by external standard method, providing absolute concentration data.

Provides analysis results such as PCA, PLS-DA, OPLS-DA, univariate tests, Random Forest, SVM screening, ROC, and more.

Adopts a rigorous quality control system to ensure data reliability.

Sample Requirements

Animal and Clinical Tissue Specimens: 200 mg/sample, flash-frozen in liquid nitrogen, stored at -80°C, and shipped with dry ice to avoid repeated freeze-thaw cycles.

Serum and Plasma: 200 μL/sample, flash-frozen in liquid nitrogen, stored at -80°C, and shipped with dry ice.

Urine: 1 mL/sample, flash-frozen in liquid nitrogen, stored at -80°C, and shipped with dry ice.

Microbes and Cells: 1×10⁷ cells/sample, flash-frozen in liquid nitrogen, stored at -80°C, and shipped with dry ice.

Fecal Samples: 200 mg/sample, flash-frozen in liquid nitrogen, stored at -80°C, and shipped with dry ice.

For other sample types, please consult our technical support or sales team.

Note: Avoid repeated freeze-thaw cycles.

Metabolomics Sample Submission Guidelines

Download our Metabolomics Sample Preparation Guide for essential instructions on proper sample collection, storage, and transport for optimal experimental results. The guide covers various sample types, including tissues, serum, urine, and cells, along with quantity requirements for untargeted and targeted metabolomics.

Download

Metabolomics Sample Submission Guidelines

* For Research Use Only. Not for use in diagnostic procedures.

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From Our Clients

"I recently used their proteomics service for a project analyzing protein interactions in yeast models. The team was very responsive and helped clarify the methodology they employed, which made me feel confident in the results. The data quality was solid, with clear identification of several key proteins involved in our study. Their thorough analysis enabled me to pinpoint specific interactions that I hadn't considered before, which significantly improved the direction of my research. I appreciate their professionalism and support throughout the process."

Sarah Thompson, University of California, Berkeley

"Our lab collaborated with them on a project studying cancer biomarkers. The proteomics analysis provided was detailed and focused, specifically highlighting the differential expression of proteins between healthy and tumor samples. Their clear explanations of the data helped my team understand the biological implications. I also appreciated their willingness to revise the reports based on our feedback, ensuring that we had everything we needed for our publication. This collaborative spirit was invaluable."

Emily Rodriguez, Stanford University

"Our lab worked with them on a project studying the effects of diet on gut microbiota using proteomics. They used a label-free quantification method to analyze proteins in fecal samples before and after dietary intervention. The results showed significant changes in protein expression linked to microbial activity. This was pivotal for our hypothesis about diet-microbiota interactions. The clarity of their data presentation made it easy for our team to integrate these findings into our ongoing research."

Dr. Lisa Wong, University of Toronto

"My experience with Creative Proteomics during the mass spectrometry analysis was excellent. We sent in human saliva and mouse brain tissue samples, which they expertly analyzed using both LC-MS and GC-MS techniques. The results were invaluable, revealing key metabolites in the saliva and identifying biomarkers linked to brain function in the brain tissue."

Dr. Emily Carter, Senior Research Scientist

"The overall service from Creative Proteomics was outstanding. They made the entire process seamless and efficient, allowing us to focus on our research. We worked with leaf and root samples from various Arabidopsis genotypes for targeted metabolomics analysis. Their thorough profiling of primary and secondary metabolites gave us important insights into how the plants respond metabolically to environmental stress."

Dr. Laura Henderson, Plant Physiologist

"We had a pleasant collaboration with Creative Proteomics on mass spectrometry analysis of lipids. They conducted a detailed analysis of lipid species, providing us with important insights into lipid metabolism and its relationship with metabolic syndrome disease states."

Dr. Sarah Mitchell, Research Scientist

Online Inquiry

Please submit a detailed description of your project. We will provide you with a customized project plan to meet your research requests. You can also send emails directly to for inquiries.

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