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KOG Annotation Analysis Service

EuKaryotic Orthologous Groups, or KOGs, is a eukaryote-specific version of the Clusters of Orthologous Groups (COGs) for the identification of ortholog and paralog proteins. KOGs database include proteins from 7 eukaryotic genomes: three animals (Homo sapiens, the fruit fly Drosophila melanogaster and the nematode Caenorhabditis elegans), one plant, Arabidopsis thaliana, two fungi (Schizosaccharomyces pombe and Saccharomyces cerevisiae), and the intracellular microsporidian parasite Encephalitozoon cuniculi. The current KOG database consists of 4852 clusters of orthologs, which include 59,838 proteins, or ~54% of the eukaryotic 110,655 gene products. Now, Scientists at Creative Proteomics are very willing to offer our customers the best KOG Annotation Analysis Service.

KOGs provides four functional groups, each of which is subdivided into KOG classifications determined by letters of the alphabet. Within each classification, groups of orthologous or paralogous proteins are assigned a KOG ID. In contrast with the coverage of the prokaryotic genomes with COGs, a significantly smaller fraction of eukaryotic genes could be classified into the KOGs; addition of novel eukaryotic genomes is expected to result in marked increase in the coverage of eukaryotic genomes with KOGs. Examination of the phyletic patterns of KOGs reveals a conserved core existed in all analyzed species and accounting for ~20% of the KOG set. This conserved portion of the KOG set is much greater than the ever-present portion of the COG set (~1% of the COGs). To some extent, this difference is probably due to the small number of involved eukaryotic genomes, but it could also reveals the relative compactness of eukaryotes as a clade and the great evolutionary stability of eukaryotic genomes.

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As one of the leading omics industry company in the world! Creative Proteomics now is opening to provide KEGG annotation analysis service for our customers. With rich experience in the field of bioinformatics, we are willing to provide our customer the most outstanding service! Contact us for all the detailed informations!

* For Research Use Only. Not for use in diagnostic procedures.

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From Our Clients

"I recently used their proteomics service for a project analyzing protein interactions in yeast models. The team was very responsive and helped clarify the methodology they employed, which made me feel confident in the results. The data quality was solid, with clear identification of several key proteins involved in our study. Their thorough analysis enabled me to pinpoint specific interactions that I hadn't considered before, which significantly improved the direction of my research. I appreciate their professionalism and support throughout the process."

Sarah Thompson, University of California, Berkeley

"Our lab collaborated with them on a project studying cancer biomarkers. The proteomics analysis provided was detailed and focused, specifically highlighting the differential expression of proteins between healthy and tumor samples. Their clear explanations of the data helped my team understand the biological implications. I also appreciated their willingness to revise the reports based on our feedback, ensuring that we had everything we needed for our publication. This collaborative spirit was invaluable."

Emily Rodriguez, Stanford University

"Our lab worked with them on a project studying the effects of diet on gut microbiota using proteomics. They used a label-free quantification method to analyze proteins in fecal samples before and after dietary intervention. The results showed significant changes in protein expression linked to microbial activity. This was pivotal for our hypothesis about diet-microbiota interactions. The clarity of their data presentation made it easy for our team to integrate these findings into our ongoing research."

Dr. Lisa Wong, University of Toronto

"My experience with Creative Proteomics during the mass spectrometry analysis was excellent. We sent in human saliva and mouse brain tissue samples, which they expertly analyzed using both LC-MS and GC-MS techniques. The results were invaluable, revealing key metabolites in the saliva and identifying biomarkers linked to brain function in the brain tissue."

Dr. Emily Carter, Senior Research Scientist

"The overall service from Creative Proteomics was outstanding. They made the entire process seamless and efficient, allowing us to focus on our research. We worked with leaf and root samples from various Arabidopsis genotypes for targeted metabolomics analysis. Their thorough profiling of primary and secondary metabolites gave us important insights into how the plants respond metabolically to environmental stress."

Dr. Laura Henderson, Plant Physiologist

"We had a pleasant collaboration with Creative Proteomics on mass spectrometry analysis of lipids. They conducted a detailed analysis of lipid species, providing us with important insights into lipid metabolism and its relationship with metabolic syndrome disease states."

Dr. Sarah Mitchell, Research Scientist

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