Nicotinamide, which is also known as niacinamide and nicotinic amide, is the amide of nicotinic acid (vitamin B3 / niacin). A more familiar term for Nicotinamide is Vitamin B3 and Nicotinamide is a water-soluble vitamin and belong to the vitamin B group. Nicotinamide is a kind of vitamin, which plays an critical role in the synthesis of components necessary for the production of ATP. Nicotinamide is the biologically active form of niacin, which is also known as nicotinic acid, can be converted to Nicotinamide in vivo. Although niacin and Nicotinamide has identical function as vitamin, the pharmacological and toxic effects occured incidental to niacin's conversion is different.
Scientists at Creative Proteomics utilize a highly quantitative method with high-performance liquid chromatography (HPLC) for the determination of Nicotinamide levels in various samples, including Various Sample Type. High-Performance Liquid Chromatography (HPLC) with UV detection is used for the determination of Nicotinamide (261 nm) levels in a lot of biological samples. This Methodology provides accurate, reliable, and reproducible results of Nicotinamide measurement, which enables us to analyze of Nicotinamide levels in vitro and in vivo.
Both Nicotinamide and nicotinic acid, are available as supplements for preventing vitamin B3 deficiency and related conditions such as pellagra. Niacinamide is used for treating diabetes and two skin conditions called bullous pemphigoid and granuloma annulare. Each of these forms of vitamin B3 is used for schizophrenia, hallucinations due to drugs, Alzheimer’s disease and age-related loss of thinking skills, chronic brain syndrome, depression, motion sickness, alcohol dependence, and fluid collection.
The Russian-Polish botanist M. Tswett is generally recognized as the first person to establish the principles of chromatography. In a paper he presented in 1906, Tswett described how he filled a glass tube with chalk powder (CaCO3) and, by allowing an ether solution of chlorophyll to flow through the chalk, separated the chlorophyll into layers of different colors. He called this technique “chromatography”. Fundamentally, chromatography is a technique used to separate the components contained in a sample. High Performance Liquid Chromatography (HPLC) is a method able to separate non-volatile, thermally unstable, and polar components separate or in a mixture. HPLC is a type of chromatography that, because of its wide application range and quantitative accuracy, is regarded as an indispensable analytical technique, particularly in the field of organic chemistry. It is also widely used as a preparation technique for the isolation and purification of target components contained in mixtures.
Nicotinamide Analysis Service at Creative Proteomics supports your research in Nicotinamide Analysis. HPLC Based Analysis Service Platform enable us at Creative Proteomics offers you a state-of-the-art Analysis Service.
Sample Type
Various Sample Type
Method
High-Performance Liquid Chromatography (HPLC) with UV detection is used for the determination of Nicotinamide (261 nm) levels in a lot of biological samples. This Methodology provides accurate, reliable, and reproducible results of Nicotinamide measurement, which enables us to analyze of Nicotinamide levels in vitro and in vivo.
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