Metabolic Flux Analysis in Fungi

Metabolic Flux Analysis in Fungi

Fungi including mushrooms, molds and yeasts are a group of organisms that are classified in their own kingdom separate from plants and animals. Fungi play an important role not only in ecosystems but also in food production, medicine and industrial applications of increasing importance. Metabolic flux analysis (MFA) has been used to analysis the metabolism of various fungal cells used in different production processes. Based on multiple measurement tools such as nuclear magnetic resonance (NMR), gas chromatography-mass spectrometry (GC-MS), and liquid chromatography-mass spectrometry (LC-MS), Creative Proteomics can help our customers to study yeasts (such as Saccharomyces cerevisiae), filamentous fungi and other fungi more comprehensively and deeply.

Our capabilities in metabolic flux analysis

• Highly complementary detection platforms
  Metabolic profiling and flux analysis require a combination of different analytical tools, and we offer complementary detection platforms such as NMR, GC-MS and LC-MS, which contribution to more accurate metabolic flux determination
• Large-scale analysis
  Our team can analyze a large numbers of samples, process large amounts of biological data, and perform large-scale analysis of metabolic activity in cells or tissues using stable isotope tracing based on strong technical capabilities and expertise
• A strong service team
  Our experts with years of experience in metabolomics, bioinformatics, statistics and diverse application areas ranging from metabolic engineering to biomedical applications can help you plan, perform, and report on your metabolic flux studies.
• Systems biology-based approaches
  The integration of technologies and competencies will enhance the elucidation of metabolomic networks and their dynamic functioning to explain and/or optimize biological processes. We support a systematic approach to accurately annotate the metabolomes of key species in order to integrate these reliable data with other functional genomics data and metabolic fluxes, and to build computational models to predict metabolic behavior.
• One-stop solution
  We provide customized metabolic flux analysis service and result interpretation integration service

Fungi MFA service at Creative Proteomics

Our fungi MFA service is designed to investigate the metabolic pathways and energy fluxes of fungal metabolism. Creative Proteomics is proud to offer NMR, GC-MS, and LC-MS-based metabolic flux analysis services to our customers worldwide. The application of these three different isotope-labeling measurement tools can provide a more accurate metabolic flux determination. Our service utilizes advanced computational techniques to simulate, predict, and analyze the metabolic networks of fungal species. We are committed to helping scientists to explore the metabolic networks of fungal species and to further improve their understanding of fungal metabolic pathways and energy fluxes.

Applications of our service

• Exploration of biosynthetic pathways of fungal metabolites
• Key enzymes in the metabolic pathways of fungal metabolite biosynthesis
• Regulatory genes of fungal metabolite biosynthesis and the regulatory factors
• Improvement of fermentation engineering technology for fungal metabolite biosynthesis

Our metabolic flux analysis service is supported by the latest knowledge in biology, bioinformatics and advanced software. If you are interested in fungi MFA analysis service, please contact us and one of our professional experts will provide you with further knowledge or consulting services.