Electrochemiluminescence Immunoassay for Virus Detection
Electrochemiluminescence immunoassay (ECLA) is a quantitative method for measurement of antigen or antibody based on the change in electrochemiluminescence (ECL) signal. As a combination of an electrochemical assay and a spectrometric assay, the ECL assay holds the advantages of both two methods. Owing to its excellent performance in the rapid detection of viruses, such as cost-effective, rapid and ultra-sensitive assay, the method has gained widespread attention. Creative Proteomics is a custom service provider in viral research with a focus on virus detection. For detection and quantification of viruses, the platform based on the highly sensitive and specific ECL-based immunoassay has been established in Creative Proteomics. Based on a professionally trained team and advanced techniques, we are dedicated to providing global customers with the optimal solutions to all their virus detection needs.
ECL-based immunoassays for virus detection
Electrochemiluminescence (ECL) is a phenomenon of light emission inducted by an excited state of species generated at the electrode surface undergoing high-energetic electron-transfer reactions. And the emitted light can be detected easily by simple instrumentation. The ECL-based detection has been successfully applied in a wide range of immunological and molecular assay systems. For virus detection, ECL-based immunoassay is an ideal choice, and possesses several advantages over chemiluminescent immunoassays (CLIA). Analogous to CLIA, ECL does not require an external light source. Therefore, the method is freed from scattered-light and luminescent impurity interferences. Although ECL is a form of CLIA, the method is more controlled and sensitive than the latter. In addition, compared to other different immunoassays (such as ELISA and fluorescence immunoassays), ECL-based immunoassay has shown reproducibility and sensitivity superiorities. The ECL-based immunoassay has represented a rapid, sensitive, and cost-effective assay for virus detection. And the method has been successfully utilized in investigation of multiple viruses, such as zika virus (ZIKV) and hepatitis B virus (HBV).
Diagram of ECL-based immunoassay for detection of viruses. (Acharya, D., et al., 2016)
Advantages of our electrochemiluminescence immunoassay (ECLA) platform
To meet the rapid, reliable and cost-effective needs of virus detection, Creative Proteomics has established a highly sensitive and specific platform based on ECL-based immunoassay. Our platform offers a seamless process to develop high-quality assays according to the specific application of our customers. Key benefits of our platform include,
- A rapid and ultra-sensitive virus detection
- A skill team with extensive assay development experience
- Personalized assay development
Creative Proteomics is a forward-looking research institute as well as a leading custom service provider in virus detection. Based on a professionally trained team, we are able to help you with high-quality and cost-effective testing service, making your project a success. In addition, our customers can contact our scientists directly for questions and learn about their project's progress at any time. If you are interested in our services, please contact us for more information. We will respond rapidly to your inquiry.
Reference
- Acharya, D., et al. (2016). "An ultrasensitive electrogenerated chemiluminescence-based immunoassay for specific detection of Zika virus." Scientific reports, 6(1), 1-11.
* For research use only.
