At present, the currently available methods for virus identification and detection are mainly based on detection of viral antigens, antiviral antibodies, or viral nucleic acid. As one of nucleic acid-based methods, real-time transcription polymerase chain reaction (RT-PCR) is the current gold standard for measurement of several viruses. However, its diagnostic accuracy is susceptible to many pre-analytical and analytical variables. Serologic testing detects antibodies against a virus, measuring the amount of antibodies produced following infection. In addition to its complementary role in nucleic acid-based methods, the method serves as a potential surveillance tool, thereby more and more attention has been paid to it. Creative Proteomics is a viral research institute with a key focus on virus detection. Based on advanced analytical devices and an excellent team of experts, we offer a broad range of serological tests available ranging from simple fluorescent neutralization test to sensitive and reliable analysis.
Plaque reduction neutralization test (PRNT) is a labor intensive, time consuming and low throughput assay. Moreover, as a conventional method, PRNT requires skilled laboratory technicians to perform, quantify and analysis results. We are dedicated to providing innovation services for global clients. Here, we are offering a reliable and fast virus neutralization test. Our service is established on fluorescence reduction neutralization assay (FRNA), and can be widely adapted for serological studies both in humans and other animals, enable to better characterize viral epidemiology, vaccine immunogenicity, antibody-based therapeutic efficacy.
Enzyme-linked immunosorbent assay (ELISA) is one of the serological detection methods which has been widely used in the detection of multiple viruses. Based on the concept of antigen-antibody reactions to detect and quantify viral proteins/particles in a solution (such as serum and plasma samples), the method has the advantages of sensitive, specific, and inexpensive. Based on our automated and flexible platform, we have the capability to detect a broad range of viral antibodies or antigens.
Electrochemiluminescence immunoassay (ECLA) is a quantitative method for measurement of antigen or antibody based on electrochemiluminescence (ECL) signal. As a combination of an electrochemical assay and a spectrometric assay, the method has various advantages, such as cost-effective, rapid and ultra-sensitive assay. To meet the growing demand for virus detection, we have established a highly sensitive and specific platform based on ECL-based immunoassay.
The development of analytical devices that enable digitalization and quantification of biological reactions provides opportunities for more advanced developments in virus detection. Based on a robust sensing platform that possesses the advances of fathomable sample separation, enrichment, ultra-sensitive readout, and anti-interference ability, Creative Proteomics is capable of providing objective, reliable, and rapid information for customers' project needs. Simply let us know about your research needs. We will propose the best strategy to best match your research objectives. Contact us right now!
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