Viral Nucleic Acid Detection Services
After virus infects the host cell, it replicates and produces large amounts of viral nucleic acid (RNA or DNA). Compared to antibodies produced later by the host immune system, the nucleic acid is the first detectable marker of viruses. Therefore, investigation of viral RNA or DNA is one of the major detection and diagnostic methods, especially suitable for an acute viral infection. For viral nucleic acids, there are developed a variety of methods, such as hybridization and amplification techniques. However, there are challenges for viral nucleic acid detection. Apart from the complex components of viral specimens, low virus abundance, but also the requirement of trained technicians and advanced instrument platform. Creative Proteomics is a forward-looking research institute as well as a leading custom provider in the field of virus detection service. We offer a series of viral nucleic acid detection services, involving amplification and sequencing techniques. Our goal is to provide rapid, reproducible and reliable assays to meet the specific needs of our customers all over the world.
Service options
DNA microarray, also called microarray or DNA chip, is a genome-based method. Since microarray allows multiplexing and has the capability to test for multiple targets simultaneously from the same specimen, the methods are well suited for identification of the virus. With the advances in microarray technologies, new platforms that are being widely adopted for detection and identification of viral targets have been established. Creative Proteomics offers microarray-based viral detection service to satisfy worldwide customers'research goals, including probe designing, sample processing, as well as microarray and data processing.
Since the application of 2009 fluA/H1N1 pandemic, real-time PCR has been widely used for virus detection, involving viral detection, quantification and typing. Real-time PCR is an innovation of PCR. As a powerful tool in microbial diagnostics, the method has numerous advantages, such as fast, sensitive and easy detection. In Creative Proteomics , we provide a one-stop service based on real-time PCR for virus detection. With our team of well-trained technicians and robust workflows, we are committed to providing our customers with the most reliable and efficient research services at a competitive price. Our service is available to analyze a variety of tissue and fluid samples for the presence of virus genomic sequences.
Metagenomic next-generation sequencing (mNGS) has emerged as a promising universal detection method for the discovery and dynamic monitoring of virus pathogens (known or unknown). The method has significant advantages in identification and genomic characterization of viruses, including high throughput and high coverage, allowing direct analysis of genetic material from environmental samples without a priori knowledge of a specific pathogen. In recent years, the discovery of many human, animal, and plant viruses has largely benefited from advances in the mNGS. With the decreasing costs of this technique, the application of it in the field of viral research is increasing. In Creative Proteomics, we provide a one-stop service of mNGS-based virus detection and identification, including sample preparation, automatic library preparation, metagenomic sequencing, bioinformatics analysis, and report interpretation. In addition, to detect a specific pathogen, mNGS-based analysis can be used in combination with RT-PCR technology to achieve complementary advantages.
The advantages of our service
- State-of-the-art facility
- Fully developed and improved analytical methods
- Ready to start your project once the contract is signed
- Fast and traceable testing for the urgent project needs
Simply let us know about your research needs. We will propose the best strategy to best match your research objectives. Contact us right now!
* For research use only.
