Integrated Proteomics and Lipidomics Analyses
Based on state-of-the-art technology and software applications, Creative Proteomics is proud to provide customized detection solutions, fast and accurate proteomics and lipidomics combination analysis services to help customers understand virus infections and host-virus interactions.
Integrated transcriptomics and proteomics analyses
Lipidomics aims to identify and quantify hundreds and thousands of lipids in biological matrices, which is a subset of metabolomics that reflects functional networks of downstream changes of the genome, transcriptome as well as proteome. More recently, a number of lipidomics studies have revealed that viral infection drastically alters the host lipidome, thus shedding light on the underlying mechanisms of viral infection. Over the past decade, proteomics studies have become prime contributors to the discovery and understanding of host-virus interactions, involving rapid and large-scale viral protein characterization, finding biomarkers to monitor the infection course, and so on. Integrating lipidomics and proteomics data to study biological samples can provide a more systematic and comprehensive analysis of biomolecular functions and regulatory mechanisms in the process of viral infection, and screen key biological pathways, proteins, and lipid metabolites, providing a basis for further virus research and related applications.
Integrated proteomics and lipidomics analyses in Creative Proteomics
As typical high-throughput functional genomics approaches, the global proteome and lipidome analysis services will lead to many interesting and new hypotheses that warrant further study. Our combined proteomics and lipidomics analysis platform is based on high-resolution tandem mass spectrometry coupled with liquid chromatography (LC-MS/MS). As a reliable partner to pharmaceutical companies and research institutions, we provide one-stop services, ranging from experimental design, sample detection to customized bioinformatics analysis to meet a variety of project needs. The general workflow for integrated proteomics and lipidomics analyses is as follows,
Lipids play crucial roles in various aspects of the virus life cycle, and the intact lipid landscape induced by viral infection is necessary for optimal viral replication. Given the critical roles of lipids virus replication and host response, lipidomics is a powerful tool that can promote our understanding of viral infections. Here, Creative Proteomics offers global proteomics and lipidomics analysis services that give insight into the intracellular processes influenced by viruses. Our success lies in constantly optimizing our services. Thanks to our long-term experience, high degree of expertise in virus research, and the application of modern technologies, we can provide high-quality and customized service to greatly accelerate our customers' project progress and success. Feel free to contact us with any questions about our services. We will be delighted to provide you with all the support we can to help establish a sustaining professional partnership.
Reference
- Jean Beltran, P. M., et al. (2017). "Proteomics and integrative omic approaches for understanding host-pathogen interactions and infectious diseases." Molecular systems biology, 13(3), 922.
* For research use only.
