Integrated Transcriptomics and Metabolomics Analyses
The metabolome is the end product of altered gene expression, which can directly and accurately reflect the pathological and physiological state of the organism. Metabolomics provides a holistic picture of host metabolism by systematically and comprehensively analyzing metabolites in living organisms and comparing changes in metabolic networks under different physiological states. Therefore, metabolomic data can complement transcriptomic and proteomic data. Metabolomics, when combined with transcriptomics, can provide a more comprehensive understanding of the biological process during viral invasion. Creative Proteomics is proud to offer a range of viral multi-omics analysis services to advance virus research. We offer integrated transcriptomics and metabolomics analyses which are part of our integrated portfolio of viral multi-omics analysis services. Based on experienced teams of scientists, researchers, and technicians, we are dedicated to providing fast turnaround, high-quality data at competitive prices for worldwide customers.
Integrated transcriptomics and metabolomics analyses
Metabolomics can provide a shot of dynamic and vulnerable host metabolites in response to specific states of viral regulation, contributing to the understanding of host-virus interactions. In addition, it can be exploited to screen biomarkers for viral disease diagnosis, prognosis, and the assessment of new drugs with applications. We have been developing metabolomics detection methods and data analysis methods for many years. Based on professional scientists and advanced platforms, we offer a range of metabolomics services from sample preparation and processing, targeted and untargeted metabolomics analysis of virus infections, to metabolic data analysis services. In addition, transcriptomics is a kind of powerful tool to identify genes, providing a global overview of complex biosynthesis processes at the transcriptional level. Our experienced scientists use advanced platforms to perform RNA-sequencing studies, non-coding RNA analysis, among others.
The workflow of our services
We provide the following analyses, including but not limited to,
| Analysis type |
Analysis content |
| Combined analysis of KEGG metabolic pathways |
Visualizing KEGG Pathways
Comparative pathway analyses
Enrichment analysis |
| Correlation analysis |
Correlation matrix heatmap
Hierarchical clustering, visualized on correlation matrix
Correlation network analysis |
| Comparative analysis of principal component analysis (PCA) |
PCA analysis of transcriptome and metabolome |
| Multivariate statistical analysis |
Partial least squares discriminant analysis (PLS-DA)
Orthogonal partial least squares discriminant analysis (OPLS-DA) |
Benefits of our services
- Professional team of scientists and advanced instruments
- Rich experience in design and analysis of multi-omics analysis
- Highly customized service to satisfy customers
- Strictly keep confidential the client's project information and experimental data
The integration of metabolomics and transcriptomics provides further insight into biological processes involved in viral infection than either approach alone. We provide one-stop services from experimental design, sample testing, data analysis, to meet a variety of testing needs. Feel free to contact us with any questions about our services. We will be delighted to provide you with all the support we can to help establish a sustaining professional partnership.
* For research use only.
