Acetylation is another common post-translational modification (PTM) of proteins and plays an important role in many
cellular physiological and pathological processes. Protein acetylation modifications are beginning to be in full
swing in the cell cycle, DNA damage research, apoptosis, autophagy, metabolism, immunity, and other fields.
Creative Proteomics has developed an acetylation analysis platform that combines multiple methods
to achieve effective identification of acetylated proteins and peptides, accurate localization and prediction of
acetylated sites, and changes in acetylated status under different physiological conditions. According to the
advantages and limitations of these methods, we can help researchers design optimal experimental studies and achieve
efficient and reliable protein acetylation analysis.
Protein acetylation analysis service
Our platform is mainly based on the advanced MS platform technology, combined with the mainstream antibody affinity
enrichment methods and high-performance liquid chromatography (HPLC), to provide a one-stop analysis service for
protein acetylation analysis. You only need to tell us your experimental purpose and send us your samples. We will
take care of all the follow-ups of your project, including protein extraction, protein digestion, acetylated peptide
enrichment, peptide separation, MS analysis, raw MS data analysis, and bioinformatics analysis. Our services are
committed to helping our customers to get insight into the biological and pathological roles of protein acetylation
and acetylated proteins.
Our services consist of four major parts:
Our service can help researchers to achieve the following goals, such as:
- Determine the presence or absence of acetylation of the target protein.
- Screen for acetylases and deacetylases.
- Identify acetylation sites.
- Study the dynamics of PTMs at the proteomic level.
- Assist in resolving the effects of acetylation on target proteins.
- Help to investigate the biological function of the target acetylation.
Workflow of acetylomics analysis service
Applications of acetylomics analysis
- Cellular biophysiological process research.
- Drug design and target research.
- Disease mechanism of action research and related marker screening.
- Plant stress and stress resistance research.
Delivery of results
- Specific process and steps of the experiment.
- Related MS parameters.
- MS images.
- Raw MS data.
- Detailed information on acetylated proteins and acetylation sites.
- Bioinformatics chart.
Creative Proteomics takes everything for the benefit of our customers as our aim and strives to
provide the best quality and efficient services for our customers. We use advanced experimental technology and
reliable methods to exchange the trust of our customers, and we believe that we can be your right-hand and
trustworthy partner in future work. If you are interested in our acetylomics analysis service, please feel free to
contact us for information. We are looking forward to cooperating with you on
your next projects.
References
- Diallo, Issa, et al. "Current trends in protein acetylation analysis." Expert Review of
Proteomics 16.2 (2019): 139-159.
- Drazic, Adrian, et al. "The world of protein acetylation." Biochimica et Biophysica Acta
(BBA)-Proteins and Proteomics 1864.10 (2016): 1372-1401.
Our products and services are for research use only.
